APC antibody (pSer2054)

Catalog No. ABIN1531521

Product Details anti-APC Antibody

Target: APC (Adenomatous Polyposis Coli (APC))

Binding Specificity: AA 2020-2069, pSer2054

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity:

APC (Phospho-Ser2054) Antibody detects endogenous levels of APC only when phosphorylated at Ser2054.

PhosphorylationH:S2054

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human APC around the phosphorylation site of Ser2054.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000

Comment:

Unigene-Number: Hs.158932 (NCBI Gene Symbol: APC)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for APC

Target: APC (Adenomatous Polyposis Coli (APC))

Alternative Name: APC (APC Products)

Background:

Synonyms: Adenomatous polyposis coli protein, adenomatous polyposis of the colon gene, APC, APC protein, DP2.5, mAPC

NCBI Gene Symbol: APC

Molecular Weight: 311 kDa

Gene ID: 324

OMIM: 135290

UniProt: P25054

Pathways: WNT Signaling, Stem Cell Maintenance, Cell-Cell Junction Organization