CXCR4 antibody (pSer339)

Catalog No. ABIN1531564

This Rabbit Polyclonal antibody specifically detects CXCR4 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for CXCR4 antibody (pSer339) (ABIN1531564)

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CXCR4 Antibody

Binding Specificity: AA 303-352, pSer339

Specificity:

CXCR4 (Phospho-Ser339) Antibody detects endogenous levels of CXCR4 only when phosphorylated at Ser339.

PhosphorylationH:S339 M:S346

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CXCR4 around the phosphorylation site of Ser339.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:20000

Comment:

Unigene-Number: Hs.593413 (NCBI Gene Symbol: CXCR4)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Alternative Name: CXCR4

Background:

Synonyms: C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, Stromal cell-derived factor 1 receptor, SDF-1 receptor, Fusin, Leukocyte-derived seven transmembrane domain receptor, LESTR, LCR1, FB22, NPYRL, HM89, CD184 antigen, CXCR4

NCBI Gene Symbol: CXCR4

Molecular Weight: 39 kDa

Gene ID: 7852

OMIM: 162643

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events