TP53BP1 antibody (pSer25)

Catalog No. ABIN1531569

Product Details anti-TP53BP1 Antibody

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Binding Specificity: AA 10-59, pSer25

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TP53BP1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Specificity:

53BP1 (Phospho-Ser25) Antibody detects endogenous levels of 53BP1 only when phosphorylated at Ser25.

PhosphorylationH:S25 M:S25 R:S30

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human 53BP1 around the phosphorylation site of Ser25.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.440968 (NCBI Gene Symbol: TP53BP1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for TP53BP1

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Alternative Name: 53BP1 (TP53BP1 Products)

Background:

Synonyms: p53-binding protein 1, P531, TP53B, TP53BP1, TRP53BP1, Tumor suppressor p53-binding protein 1

NCBI Gene Symbol: TP53BP1

Molecular Weight: 213 kDa

Gene ID: 7158

OMIM: 605230

UniProt: Q12888

Pathways: DNA Damage Repair