Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

TP53BP1 antibody (pSer25, pSer29)

TP53BP1 Reactivity: Human, Mouse, Rat ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
Pubmed (1 reference)
Catalog No. ABIN682993
$352.31
Plus shipping costs $45.00
100 μL
Shipping to: United States
Delivery in 4 to 6 Business Days
  • Target See all TP53BP1 Antibodies
    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
    Binding Specificity
    • 24
    • 17
    • 15
    • 12
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer25, pSer29
    Reactivity
    • 95
    • 56
    • 50
    • 10
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 98
    • 11
    • 1
    • 1
    Rabbit
    Clonality
    • 93
    • 18
    Polyclonal
    Conjugate
    • 58
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TP53BP1 antibody is un-conjugated
    Application
    • 45
    • 27
    • 26
    • 26
    • 26
    • 21
    • 16
    • 14
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This phosphorylated site is the same in Mouse and homologous to p53BP1 Ser30 + Ser34 in Rat.
    Predicted Reactivity
    Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human p53BP1 around the phosphorylation site of Ser25/29
    Isotype
    IgG
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Cai, Cao, Zhang, Xue, Zhang, Zhou, Zhou, Sun, Fu: "Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis." in: The Journal of biological chemistry, Vol. 290, Issue 32, pp. 19967-75, (2015) (PubMed).

  • Target
    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
    Alternative Name
    p53BP1 + (TP53BP1 Products)
    Synonyms
    TP53BP1, MGC160112, 53BP1, Tp53bp1, m53BP1, p202, Trp53bp1, tumor protein p53 binding protein 1, tumor suppressor p53-binding protein 1, tumor protein p53 binding protein 1 (predicted), 5 prime, transformation related protein 53 binding protein 1, TP53BP1, tp53bp1, LOC100550605, Trp53bp1, Tp53bp1
    Background

    Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.

    Subcellular location: Nucleus

    Synonyms: p202, 53BP1, Tumor suppressor p53-binding protein 1, p53-binding protein 1, p53BP1, TP53BP1

    Gene ID
    7158
    UniProt
    Q12888
    Pathways
    DNA Damage Repair
You are here:
Support