FAS antibody (pTyr291)

Catalog No. ABIN1531598

Product Details anti-FAS Antibody

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Binding Specificity: AA 257-306, pTyr291

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAS antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Specificity:

FAS (Phospho-Tyr291) Antibody detects endogenous levels of FAS only when phosphorylated at Tyr291.

PhosphorylationH:Y291

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FAS around the phosphorylation site of Tyr291.

Isotype: IgG

Application Details

Application Notes: IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.244139 (NCBI Gene Symbol: FAS)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for FAS

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Alternative Name: FAS (FAS Products)

Background:

Synonyms: Apo-1, apoptosis-mediating surface antigen FAS, CD95, FasL receptor, TNFRSF6, TNR6, tumor necrosis factor receptor superfamily member 6, tumor necrosis factor receptor superfamily, member 6 (FAS)

NCBI Gene Symbol: FAS

Molecular Weight: 37 kDa

Gene ID: 355

OMIM: 134637

UniProt: P25445

Pathways: p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity