HDAC3 antibody (pSer424)

Catalog No. ABIN1531607

The Rabbit Polyclonal anti-HDAC3 antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect HDAC3 in samples from Human, Mouse and Rat.

Quick Overview for HDAC3 antibody (pSer424) (ABIN1531607)

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-HDAC3 Antibody

Binding Specificity: AA 379-428, pSer424

Specificity:

HDAC3 (Phospho-Ser424) Antibody detects endogenous levels of HDAC3 only when phosphorylated at Ser424.

PhosphorylationH:S424 M:S424 R:S424

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HDAC3 around the phosphorylation site of Ser424.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.519632 (NCBI Gene Symbol: HDAC3)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for HDAC3

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Alternative Name: HDAC3

Background:

Synonyms: HD3, Histone deacetylase 3, RPD3-2, SMAP45

NCBI Gene Symbol: HDAC3

Molecular Weight: 48 kDa

Gene ID: 8841

OMIM: 605166

UniProt: O15379

Pathways: Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development