NMDAR2A + 2B antibody (pTyr1246)
The Rabbit Polyclonal anti-NMDAR2A + 2B antibody (ABIN1531617) specifically detects NMDAR2A + 2B in ELISA, IF and IHC.
The antibody is reactive with Rat, Human and Mouse samples.
Catalog No. ABIN1531617
$341.00
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Quick Overview for NMDAR2A + 2B antibody (pTyr1246) (ABIN1531617)
Target
NMDAR2A + 2B (GRIN2A/B)
(Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2A/B (GRIN2A/B))
Reactivity
Rat, Human, Mouse
Host
Rabbit
Clonality
Polyclonal
Conjugate
This NMDAR2A + 2B antibody is un-conjugated
Application
ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
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Binding Specificity
- AA 1216-1265, pTyr1246
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Specificity
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NMDAR2A/B (Phospho-Tyr1246/1252) Antibody detects endogenous levels of NMDAR2A/B only when phosphorylated at Tyr1246/1252.
PhosphorylationH:Y1246/Y1252 M:Y1246/Y1252 R:Y1246/Y1252
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Purification
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Purity
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human NMDAR2A/B around the phosphorylation site of Tyr1246/1252.
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Isotype
- IgG
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Application Notes
- IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:10000
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Comment
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Unigene-Number: Hs.411472, Hs.567280, Hs.654430 (NCBI Gene Symbol: GRIN2A)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable at -20°C for at least 1 year.
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Expiry Date
- 12 months
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- NMDAR2A + 2B (GRIN2A/B) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2A/B (GRIN2A/B))
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Background
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Synonyms: Glutamate [NMDA] receptor subunit epsilon 1 precursor, GRIN2A, N-methyl D-aspartate receptor subtype 2A, N-methyl-D-aspartate receptor subtype 2A, NMDAR2AGlutamate [NMDA] receptor subunit epsilon 1, NMDE1, NME1, NR2A
NCBI Gene Symbol: GRIN2A
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Molecular Weight
- 165 kDa
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Gene ID
- 2903, 2904
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OMIM
- 138253
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UniProt
- Q12879, Q13224
Target
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