S1PR1 antibody (pThr236)

Catalog No. ABIN1531727

The Rabbit Polyclonal anti-S1PR1 antibody is suitable to detect S1PR1 in samples from Human, Mouse and Rat. It has been validated for ELISA and IF.

Quick Overview for S1PR1 antibody (pThr236) (ABIN1531727)

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S1PR1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-S1PR1 Antibody

Binding Specificity: AA 206-255, pThr236

Specificity:

S1P Receptor EDG1 (Phospho-Thr236) Antibody detects endogenous levels of S1P Receptor EDG1 only when phosphorylated at Thr236.

PhosphorylationH:T236 M:T236 R:T237

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human S1P Receptor EDG1 around the phosphorylation site of Thr236.

Isotype: IgG

Application Details

Application Notes: IF: 1:100~1:500 ELISA: 1:10000

Comment:

Unigene-Number: Hs.154210 (NCBI Gene Symbol: S1PR1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for S1PR1

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Alternative Name: S1P Receptor EDG1

Background:

Synonyms: Sphingosine 1-phosphate receptor Edg-1, Sphingosine 1-phosphate receptor 1, S1P1, EDG1

NCBI Gene Symbol: S1PR1

Molecular Weight: 42 kDa

Gene ID: 1901

OMIM: 601974

UniProt: P21453

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2