ARHGEF2 antibody (pSer885)

Catalog No. ABIN1531753

This Rabbit Polyclonal antibody specifically detects ARHGEF2 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ARHGEF2 antibody (pSer885) (ABIN1531753)

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ARHGEF2 Antibody

Binding Specificity: AA 851-900, pSer885

Specificity:

Rho/Rac Guanine Nucleotide Exchange Factor 2 (Phospho-Ser885) Antibody detects endogenous levels of Rho/Rac Guanine Nucleotide Exchange Factor 2 only when phosphorylated at Ser885.

PhosphorylationH:S885 M:S885 R:S885

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Rho/Rac Guanine Nucleotide Exchange Factor 2 around the phosphorylation site of Ser885.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:5000

Comment:

Unigene-Number: Hs.655209 (NCBI Gene Symbol: ARHGEF2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for ARHGEF2

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Alternative Name: rho/rac Guanine Nucleotide Exchange Factor 2

Background:

Synonyms: GEF-H1, GEFH1, Guanine nucleotide exchange factor GEF-H1, proliferating cell nucleolar antigen p40, rho/rac guanine nucleotide exchange factor 2

NCBI Gene Symbol: ARHGEF2

Molecular Weight: 111 kDa

Gene ID: 9181

OMIM: 607560

UniProt: Q92974

Pathways: Negative Regulation of intrinsic apoptotic Signaling