LIM Domain Kinase 1 antibody (pThr508)

Catalog No. ABIN1531896

This anti-LIM Domain Kinase 1 antibody is a Rabbit Polyclonal antibody detecting LIM Domain Kinase 1 in WB, ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for LIM Domain Kinase 1 antibody (pThr508) (ABIN1531896)

Target: LIM Domain Kinase 1 (LIMK1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIM Domain Kinase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-LIM Domain Kinase 1 Antibody

Binding Specificity: AA 471-520, pThr508

Specificity:

LIMK1 (Phospho-Thr508) Antibody detects endogenous levels of LIMK1 only when phosphorylated at Thr508.

PhosphorylationH:T508 M:T508 R:T508

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human LIMK1 around the phosphorylation site of Thr508.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Comment:

Unigene-Number: Hs.647035 (NCBI Gene Symbol: LIMK1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for LIM Domain Kinase 1

Target: LIM Domain Kinase 1 (LIMK1)

Alternative Name: LIMK1

Background:

Synonyms: kinase LIMK1, KIZ-1, LIM domain kinase 1, LIMK, LIMK-1

NCBI Gene Symbol: LIMK1

Molecular Weight: 72 kDa

Gene ID: 3984

OMIM: 194050

UniProt: P53667

Pathways: Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events