SNRPE antibody (pSer446)

Catalog No. ABIN1532038

The Rabbit Polyclonal anti-SNRPE antibody has been validated for WB, IHC and ELISA. It is suitable to detect SNRPE in samples from Human and Mouse.

Quick Overview for SNRPE antibody (pSer446) (ABIN1532038)

Target: SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNRPE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-SNRPE Antibody

Binding Specificity: AA 411-460, pSer446

Specificity:

B-RAF (Phospho-Ser446) Antibody detects endogenous levels of B-RAF only when phosphorylated at Ser446.

PhosphorylationH:S446 M:S483

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human B-RAF around the phosphorylation site of Ser446.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Comment:

Unigene-Number: Hs.550061 (NCBI Gene Symbol: BRAF1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for SNRPE

Target: SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

Alternative Name: B-RAF

Background:

Synonyms: B-RAF, B-RAF proto-oncogene serine/threonine-protein kinase, B-Raf proto-oncogene serine/threonine-protein kinase, BRAF, BRAF1, c-RMIL, kinase B-Raf, p94, RAFB1, RMIL, RMIL serine/threonine-protein kinase, v-Raf murine sarcoma viral oncogene homolog B1

NCBI Gene Symbol: BRAF1

Molecular Weight: 84 kDa

Gene ID: 673

OMIM: 114500

UniProt: P15056

Pathways: Ribonucleoprotein Complex Subunit Organization, Hepatitis C