RIPK2 antibody (pSer176)

Catalog No. ABIN1532078

This anti-RIPK2 antibody is a Rabbit Polyclonal antibody detecting RIPK2 in WB, ELISA and IHC. Suitable for Human and Mouse.

Quick Overview for RIPK2 antibody (pSer176) (ABIN1532078)

Target: RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIPK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-RIPK2 Antibody

Binding Specificity: AA 146-195, pSer176

Specificity:

RIPK2 (Phospho-Ser176) Antibody detects endogenous levels of RIPK2 only when phosphorylated at Ser176.

PhosphorylationH:S176 M:S176

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human RIPK2 around the phosphorylation site of Ser176.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000

Comment:

Unigene-Number: Hs.103755 (NCBI Gene Symbol: RIPK2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for RIPK2

Target: RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))

Alternative Name: RIPK2

Background:

Synonyms: CARD-containing IL-1 beta ICE-kinase, CARD-containing interleukin-1 beta converting enzyme associated kinase, CARDIAK, kinase RIPK2, Receptor-interacting protein 2, Receptor-interacting serine/threonine protein kinase 2, RICK, RIP-2, RIP-like interacting

NCBI Gene Symbol: RIPK2

Molecular Weight: 61 kDa

Gene ID: 8767

OMIM: 603455

UniProt: O43353

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades