Cadherin 5 antibody (pTyr731)

Catalog No. ABIN1532109

This Rabbit Polyclonal antibody specifically detects Cadherin 5 in WB, IHC and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Cadherin 5 antibody (pTyr731) (ABIN1532109)

Target: Cadherin 5 (CDH5)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Cadherin 5 Antibody

Binding Specificity: AA 697-746, pTyr731

Specificity:

VE-Cadherin (Phospho-Tyr731) Antibody detects endogenous levels of VE-Cadherin only when phosphorylated at Tyr731.

PhosphorylationH:Y731 M:Y731

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human VE-Cadherin around the phosphorylation site of Tyr731.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000

Comment:

Unigene-Number: Hs.76206 (NCBI Gene Symbol: CDH5)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Cadherin 5

Target: Cadherin 5 (CDH5)

Alternative Name: VE-Cadherin

Background:

Synonyms: 7B4 antigen, CADH5, Cadherin-5, CD144 antigen, Vascular endothelial-cadherin precursor, VE-cadherin

NCBI Gene Symbol: CDH5

Molecular Weight: 87 kDa

Gene ID: 1003

OMIM: 601120

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2