GAB2 antibody (pSer623)

Catalog No. ABIN1532145

This Rabbit Polyclonal antibody specifically detects GAB2 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GAB2 antibody (pSer623) (ABIN1532145)

Target: GAB2 (GRB2-Associated Binding Protein 2 (GAB2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAB2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-GAB2 Antibody

Binding Specificity: AA 589-638, pSer623

Specificity:

Gab2 (Phospho-Ser623) Antibody detects endogenous levels of Gab2 only when phosphorylated at Ser623.

PhosphorylationH:S623 M:S612 R:S612

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Gab2 around the phosphorylation site of Ser623.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.429434 (NCBI Gene Symbol: GAB2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for GAB2

Target: GAB2 (GRB2-Associated Binding Protein 2 (GAB2))

Alternative Name: Gab2

Background:

Synonyms: GRB2-associated-binding protein 2, Growth factor receptor bound protein 2-associated protein 2, GRB2-associated binder 2, pp100, KIAA0571

NCBI Gene Symbol: GAB2

Molecular Weight: 74 kDa

Gene ID: 9846

OMIM: 606203

UniProt: Q9UQC2

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effect