MKNK1 antibody (pThr385)

Catalog No. ABIN1532155

The Rabbit Polyclonal anti-MKNK1 antibody has been validated for WB, ELISA and IHC. It is suitable to detect MKNK1 in samples from Human, Mouse and Rat.

Quick Overview for MKNK1 antibody (pThr385) (ABIN1532155)

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKNK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MKNK1 Antibody

Binding Specificity: AA 351-400, pThr385

Specificity:

Mnk1 (Phospho-Thr385) Antibody detects endogenous levels of Mnk1 only when phosphorylated at Thr385.

PhosphorylationH:T385 M:T344 R:T332

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Mnk1 around the phosphorylation site of Thr385.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000

Comment:

Unigene-Number: Hs.371594 (NCBI Gene Symbol: MKNK1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for MKNK1

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Alternative Name: Mnk1

Background:

Synonyms: kinase Mnk1, Map kinase interacting kinase, MAP kinase signal-integrating kinase 1, MAP kinase-interacting serine/threonine kinase 1, MKNK1

NCBI Gene Symbol: MKNK1

Molecular Weight: 51 kDa

Gene ID: 8569

OMIM: 606724

UniProt: Q9BUB5

Pathways: MAPK Signaling, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor