CNOT2 antibody (pSer101)

Catalog No. ABIN1532161

The Rabbit Polyclonal anti-CNOT2 antibody has been validated for ELISA and IHC. It is suitable to detect CNOT2 in samples from Human, Mouse and Rat.

Quick Overview for CNOT2 antibody (pSer101) (ABIN1532161)

Target: CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-CNOT2 Antibody

Binding Specificity: AA 67-116, pSer101

Specificity:

CNOT2 (Phospho-Ser101) Antibody detects endogenous levels of CNOT2 only when phosphorylated at Ser101.

PhosphorylationH:S101 M:S101 R:S16

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CNOT2 around the phosphorylation site of Ser101.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.133350 (NCBI Gene Symbol: CNOT2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for CNOT2

Target: CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))

Alternative Name: CNOT2

Background:

Synonyms: CCR4-associated factor 2, CCR4-NOT transcription complex subunit 2, CCR4-NOT transcription complex, subunit 2, CDC36, CNOT2, HSPC131, MSTP046, NOT2 (negative regulator of transcription 2, yeast) homolog, NOT2H

NCBI Gene Symbol: CNOT2

Molecular Weight: 59 kDa

Gene ID: 4848

OMIM: 604909

UniProt: Q9NZN8

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance