BTK antibody (AA 188-237)

Catalog No. ABIN1532229

The Rabbit Polyclonal anti-BTK antibody has been validated for WB, ELISA and IHC. It is suitable to detect BTK in samples from Human, Mouse and Rat.

Quick Overview for BTK antibody (AA 188-237) (ABIN1532229)

Target: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-BTK Antibody

Binding Specificity: AA 188-237

Specificity:

BTK Antibody detects endogenous levels of total BTK protein.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human BTK.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000

Comment:

Unigene-Number: Hs.159494 (NCBI Gene Symbol: BTK)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for BTK

Target: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Alternative Name: BTK

Background:

Synonyms: AGMX1, ATK, Agammaglobulinaemia tyrosine kinase, B cell progenitor kinase, BPK, Bruton's tyrosine kinase, Kinase EMB, kinase Btk

NCBI Gene Symbol: BTK

Molecular Weight: 76 kDa

Gene ID: 695

OMIM: 300300

UniProt: Q06187

Pathways: Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling