TRHR antibody (AA 195-244)

Catalog No. ABIN1536075

This Rabbit Polyclonal antibody specifically detects TRHR in WB, ELISA and IF. It exhibits reactivity toward Human, Rat and Mouse and has been mentioned in 2+ publications.

Quick Overview for TRHR antibody (AA 195-244) (ABIN1536075)

Target: TRHR (Thyrotropin-Releasing Hormone Receptor (TRHR))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRHR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-TRHR Antibody

Binding Specificity: AA 195-244

Specificity:

TRHR Antibody detects endogenous levels of total TRHR protein.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TRHR.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:20000

Comment:

Unigene-Number: Hs.3022 (NCBI Gene Symbol: TRHR)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

References for anti-TRHR antibody (ABIN1536075)

Liu, Li, Ha, Qi, Duan, Yang: "The PI3K/Akt and ERK pathways elevate thyroid hormone receptor ?1 and TRH receptor to decrease thyroid hormones after exposure to PCB153 and p,p'-DDE." in: Chemosphere, Vol. 118, pp. 229-38, (2014) (PubMed).

Liu, Ha, Cui, Wang, Yan, Fu, Quan, Zhou, Yang: "JNK pathway decreases thyroid hormones via TRH receptor: a novel mechanism for disturbance of thyroid hormone homeostasis by PCB153." in: Toxicology, Vol. 302, Issue 1, pp. 68-76, (2012) (PubMed).

Target Details for TRHR

Target: TRHR (Thyrotropin-Releasing Hormone Receptor (TRHR))

Alternative Name: TRHR

Background:

Synonyms: Thyrotropin-releasing hormone receptor, TRH-R, Thyroliberin receptor, TRHR

NCBI Gene Symbol: TRHR

Molecular Weight: 45 kDa

Gene ID: 7201

OMIM: 188545

UniProt: P34981