MCF2L antibody (C-Term)

Catalog No. ABIN1536637

This Rabbit Polyclonal antibody specifically detects MCF2L in WB. It exhibits reactivity toward Human.

Quick Overview for MCF2L antibody (C-Term) (ABIN1536637)

Target: MCF2L (MCF.2 Cell Line Derived Transforming Sequence-Like (MCF2L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCF2L antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB38890

Product Details anti-MCF2L Antibody

Binding Specificity: AA 1049-1075, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MCF2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1049-1075 amino acids from the C-terminal region of human MCF2L.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MCF2L Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for MCF2L

Target: MCF2L (MCF.2 Cell Line Derived Transforming Sequence-Like (MCF2L))

Alternative Name: MCF2L

Background: Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.

Molecular Weight: 128109

Gene ID: 23263

NCBI Accession: NP_001106203, NP_079255

UniProt: O15068

Pathways: Neurotrophin Signaling Pathway, Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis