MCF2L antibody (AA 850-980)

Catalog No. ABIN7154651

Product Details anti-MCF2L Antibody

Target: MCF2L (MCF.2 Cell Line Derived Transforming Sequence-Like (MCF2L))

Binding Specificity: AA 850-980

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCF2L antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Guanine nucleotide exchange factor DBS protein (850-980AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MCF2L

Target: MCF2L (MCF.2 Cell Line Derived Transforming Sequence-Like (MCF2L))

Alternative Name: MCF2L (MCF2L Products)

Synonyms: ARHGEF14 antibody, DBS antibody, OST antibody, Ost antibody, mcf 2l antibody, MCF2L antibody, NV11503 antibody, dbs antibody, ost antibody, arhgef14 antibody, C130040G20Rik antibody, Dbs antibody, mKIAA0362 antibody, MCF.2 cell line derived transforming sequence like antibody, MCF.2 cell line derived transforming sequence-like antibody, guanine nucleotide exchange factor DBS antibody, mcf.2 transforming sequence-like antibody, MCF2L antibody, Mcf2l antibody, LOC100122691 antibody, mcf2l.2 antibody, mcf2l antibody

Background:

Background: Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (By similarity). Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42 (PubMed:15157669).

Aliases: ARHGEF 14 antibody, DBL''s big sister antibody, DBS antibody, FLJ12122 antibody, Guanine nucleotide exchange factor DBS antibody, KIAA0362 antibody, MCF 2L antibody, MCF.2 cell line derived transforming sequence like antibody, MCF.2 transforming sequence-like antibody, MCF2 like protein antibody, MCF2 transforming sequence like protein antibody, MCF2-transforming sequence-like protein antibody, Mcf2l antibody, MCF2L_HUMAN antibody, OST antibody, OST oncogene antibody

UniProt: O15068

Pathways: Neurotrophin Signaling Pathway, Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis