PER1 antibody (C-Term)

Catalog No. ABIN1536671

The Rabbit Polyclonal anti-PER1 antibody has been validated for WB. It is suitable to detect PER1 in samples from Human. There is 1 publication available.

Quick Overview for PER1 antibody (C-Term) (ABIN1536671)

Target: PER1 (Period Homolog 1 (Drosophila) (PER1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PER1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB36279

Product Details anti-PER1 Antibody

Binding Specificity: AA 1156-1183, C-Term

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PER1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1156-1183 amino acids from the C-terminal region of human PER1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PER1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

References for anti-PER1 antibody (ABIN1536671)

Hwang-Verslues, Chang, Jeng, Kuo, Chiang, Chang, Hsieh, Su, Lin, Abbondante, Yang, Hsu, Yu, Chang, Shew, Lee, Lee: "Loss of corepressor PER2 under hypoxia up-regulates OCT1-mediated EMT gene expression and enhances tumor malignancy." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 30, pp. 12331-6, (2013) (PubMed).

Target Details for PER1

Target: PER1 (Period Homolog 1 (Drosophila) (PER1))

Alternative Name: PER1

Background: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. Alternative splicing has been observed in this gene, however, these variants have not been fully described.

Molecular Weight: 136212

Gene ID: 5187

NCBI Accession: NP_002607

UniProt: O15534

Pathways: Photoperiodism