AP3M1 antibody (C-Term)

Catalog No. ABIN1537256

The Rabbit Polyclonal anti-AP3M1 antibody is suitable to detect AP3M1 in samples from Human. It has been validated for WB.

Quick Overview for AP3M1 antibody (C-Term) (ABIN1537256)

Target: AP3M1 (Adaptor-Related Protein Complex 3, mu 1 Subunit (AP3M1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3M1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB21385

Product Details anti-AP3M1 Antibody

Binding Specificity: AA 390-418, C-Term

Predicted Reactivity: B, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AP3M1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 390-418 amino acids from the C-terminal region of human AP3M1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: AP3M1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for AP3M1

Target: AP3M1 (Adaptor-Related Protein Complex 3, mu 1 Subunit (AP3M1))

Alternative Name: AP3M1

Background: The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed.

Molecular Weight: 46939

Gene ID: 26985

NCBI Accession: NP_036227, NP_996895

UniProt: Q9Y2T2