BSDC1 antibody (C-Term)

Catalog No. ABIN1537276

This Rabbit Polyclonal antibody specifically detects BSDC1 in WB. It exhibits reactivity toward Human.

Quick Overview for BSDC1 antibody (C-Term) (ABIN1537276)

Target: BSDC1 (BSD Domain Containing 1 (BSDC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BSDC1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB36583

Product Details anti-BSDC1 Antibody

Binding Specificity: AA 397-425, C-Term

Predicted Reactivity: B, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BSDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 397-425 amino acids from the C-terminal region of human BSDC1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: BSDC1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for BSDC1

Target: BSDC1 (BSD Domain Containing 1 (BSDC1))

Alternative Name: BSDC1

Background: BSDC1 is a 430 amino acid protein encoded by a gene mapping to chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Molecular Weight: 47163

Gene ID: 55108

NCBI Accession: NP_001137360, NP_001137361, NP_001137362, NP_060515

UniProt: Q9NW68