TLK1 antibody (C-Term)

Catalog No. ABIN1537558

This Rabbit Polyclonal antibody specifically detects TLK1 in WB. It exhibits reactivity toward Mouse.

Quick Overview for TLK1 antibody (C-Term) (ABIN1537558)

Target: TLK1 (Tousled-Like Kinase 1 (TLK1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLK1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB37154

Product Details anti-TLK1 Antibody

Binding Specificity: AA 701-728, C-Term

Predicted Reactivity: H

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Tlk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 701-728 amino acids from the C-terminal region of mouse Tlk1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Mouse Tlk1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for TLK1

Target: TLK1 (Tousled-Like Kinase 1 (TLK1))

Alternative Name: Tlk1

Background: Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly (By similarity). Isoform 3 protects the cells from the ionizing radiation by faciliting the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10' (By similarity).

Molecular Weight: 86624

Gene ID: 228012

NCBI Accession: NP_766252

UniProt: Q8C0V0