Fatty Acid Synthase antibody (AA 942-973)

Catalog No. ABIN1537694

The Mouse Monoclonal anti-Fatty Acid Synthase antibody is suitable to detect Fatty Acid Synthase in samples from Human. It has been validated for WB and IF.

Quick Overview for Fatty Acid Synthase antibody (AA 942-973) (ABIN1537694)

Target: Fatty Acid Synthase (FASN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fatty Acid Synthase antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 497CT15-2-5

Product Details anti-Fatty Acid Synthase Antibody

Binding Specificity: AA 942-973

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This FASN antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 942-973 amino acids from the Central region of human FASN.

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:500-1:2000. IF: 1:200. IF: 1:25. IF: 1:25. WB: 1:100. WB: 1:8000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: FASN Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Alternative Name: FASN

Background: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Molecular Weight: 273427

Gene ID: 2194

NCBI Accession: NP_004095

UniProt: P49327

Pathways: AMPK Signaling