Myotilin antibody (AA 127-155)
Quick Overview for Myotilin antibody (AA 127-155) (ABIN1537809)
Target
See all Myotilin (MYOT) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 127-155
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This MYOT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-155 amino acids from the Central region of human MYOT.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- MYOT Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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Expiry Date
- 6 months
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- Myotilin (MYOT)
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Alternative Name
- MYOT
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Background
- This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
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Molecular Weight
- 55395
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Gene ID
- 9499
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NCBI Accession
- NP_001129412, NP_006781
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UniProt
- Q9UBF9
Target
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