FBXO8 antibody (AA 168-195)

Catalog No. ABIN1537932

This anti-FBXO8 antibody is a Rabbit Polyclonal antibody detecting FBXO8 in WB. Suitable for Mouse.

Quick Overview for FBXO8 antibody (AA 168-195) (ABIN1537932)

Target: FBXO8 (F-Box Protein 8 (FBXO8))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO8 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB37321

Product Details anti-FBXO8 Antibody

Binding Specificity: AA 168-195

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FBXO8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-195 amino acids from the Central region of human FBXO8.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: FBXO8 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for FBXO8

Target: FBXO8 (F-Box Protein 8 (FBXO8))

Alternative Name: FBXO8

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.

Molecular Weight: 37068

Gene ID: 26269

NCBI Accession: NP_036312

UniProt: Q9NRD0