FZD7 antibody (AA 202-229)

Catalog No. ABIN1538054

The Rabbit Polyclonal anti-FZD7 antibody has been validated for WB. It is suitable to detect FZD7 in samples from Human.

Quick Overview for FZD7 antibody (AA 202-229) (ABIN1538054)

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD7 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB25727

Product Details anti-FZD7 Antibody

Binding Specificity: AA 202-229

Predicted Reactivity: C, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FZD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-229 amino acids from the Central region of human FZD7.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: FZD7 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for FZD7

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Alternative Name: FZD7

Background: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

Molecular Weight: 63620

Gene ID: 8324

NCBI Accession: NP_003498

UniProt: O75084

Pathways: WNT Signaling, Stem Cell Maintenance