PPP4R2 antibody (AA 228-254)

Catalog No. ABIN1538128

This Rabbit Polyclonal antibody specifically detects PPP4R2 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for PPP4R2 antibody (AA 228-254) (ABIN1538128)

Target: PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP4R2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB37606

Product Details anti-PPP4R2 Antibody

Binding Specificity: AA 228-254

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PPP4R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-254 amino acids from the Central region of human PPP4R2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PPP4R2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for PPP4R2

Target: PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))

Alternative Name: PPP4R2

Background: Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.

Molecular Weight: 46898

Gene ID: 151987

NCBI Accession: NP_777567

UniProt: Q9NY27