LIM Domain Binding 3 Protein antibody (AA 235-262)

Catalog No. ABIN1538145

This anti-LIM Domain Binding 3 Protein antibody is a Rabbit Polyclonal antibody detecting LIM Domain Binding 3 Protein in WB. Suitable for Human.

Quick Overview for LIM Domain Binding 3 Protein antibody (AA 235-262) (ABIN1538145)

Target: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIM Domain Binding 3 Protein antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB36787

Product Details anti-LIM Domain Binding 3 Protein Antibody

Binding Specificity: AA 235-262

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LDB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-262 amino acids from the Central region of human LDB3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: LDB3 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for LIM Domain Binding 3 Protein

Target: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Alternative Name: LDB3

Background: This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified, all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains. [provided by RefSeq].

Molecular Weight: 77135

Gene ID: 11155

NCBI Accession: NP_001073583, NP_001073584, NP_001073585, NP_001165081, NP_001165082, NP_009009

UniProt: O75112