ATP6V1C2 antibody (AA 276-304)

Catalog No. ABIN1538227

This Rabbit Polyclonal antibody specifically detects ATP6V1C2 in WB. It exhibits reactivity toward Human.

Quick Overview for ATP6V1C2 antibody (AA 276-304) (ABIN1538227)

Target: ATP6V1C2 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C2 (ATP6V1C2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V1C2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB37563

Product Details anti-ATP6V1C2 Antibody

Binding Specificity: AA 276-304

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATP6V1C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the Central region of human ATP6V1C2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: ATP6V1C2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for ATP6V1C2

Target: ATP6V1C2 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C2 (ATP6V1C2))

Alternative Name: ATP6V1C2

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.

Molecular Weight: 48759

Gene ID: 245973

NCBI Accession: NP_001034451, NP_653184

UniProt: Q8NEY4

Pathways: Transition Metal Ion Homeostasis, Proton Transport