PCDHA1 antibody (AA 288-316)

Catalog No. ABIN1538249

The Rabbit Polyclonal anti-PCDHA1 antibody has been validated for WB. It is suitable to detect PCDHA1 in samples from Human.

Quick Overview for PCDHA1 antibody (AA 288-316) (ABIN1538249)

Target: PCDHA1 (Protocadherin alpha 1 (PCDHA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHA1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB32960

Product Details anti-PCDHA1 Antibody

Binding Specificity: AA 288-316

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCDHA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-316 amino acids from the Central region of human PCDHA1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PCDHA1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for PCDHA1

Target: PCDHA1 (Protocadherin alpha 1 (PCDHA1))

Alternative Name: PCDHA1

Background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Molecular Weight: 102952

Gene ID: 56147

NCBI Accession: NP_061723, NP_113598, NP_113599

UniProt: Q9Y5I3