MRGBP antibody (AA 46-75)

Catalog No. ABIN1538431

This Rabbit Polyclonal antibody specifically detects MRGBP in WB. It exhibits reactivity toward Human.

Quick Overview for MRGBP antibody (AA 46-75) (ABIN1538431)

Target: MRGBP (MRG-Binding Protein (MRGBP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRGBP antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB38302

Product Details anti-MRGBP Antibody

Binding Specificity: AA 46-75

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MRGBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the Central region of human MRGBP.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MRGBP Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for MRGBP

Target: MRGBP (MRG-Binding Protein (MRGBP))

Alternative Name: MRGBP

Background: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome -DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.

Molecular Weight: 22417

Gene ID: 55257

NCBI Accession: NP_060740

UniProt: Q9NV56