DR1 antibody (AA 83-112)

Catalog No. ABIN1538651

The Rabbit Polyclonal anti-DR1 antibody has been validated for WB. It is suitable to detect DR1 in samples from Human and Mouse.

Quick Overview for DR1 antibody (AA 83-112) (ABIN1538651)

Target: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DR1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB37581

Product Details anti-DR1 Antibody

Binding Specificity: AA 83-112

Predicted Reactivity: C, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-112 amino acids from the Central region of human DR1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: DR1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for DR1

Target: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Alternative Name: DR1

Background: This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

Molecular Weight: 19444

Gene ID: 1810

NCBI Accession: NP_001929

UniProt: Q01658