DR1 antibody (TATA-Binding Protein-Associated Phosphoprotein) (N-Term)

Details for Product anti-DR1 Antibody No. ABIN2780386, Supplier: Log in to see
Antigen
  • BG:DS00929.3
  • CG4185
  • Dmel\\CG4185
  • Dr1
  • NC2 beta
  • Nc2b
  • dDr1
  • dNC2
  • wu:fj15f04
  • zgc:152914
  • 1700121L09Rik
  • Dr1l
  • NC2
  • NC2beta
  • NC2-BETA
  • Negative Cofactor 2beta
  • TATA-BINDING PROTEIN-ASSOCIATED PHOSPHOPROTEIN
  • TATA-binding protein-associated phosphoprotein
  • putative tata-binding protein-associated phosphoprotein
  • down-regulator of transcription 1
  • down-regulator of transcription 1, TBP-binding (negative cofactor 2)
  • NC2beta
  • ECU11_0730
  • EDI_229030
  • PTRG_08168
  • Smp_160150
  • EBI_26279
  • EBI_23074
  • VDBG_02216
  • dr1
  • Dr1
  • DR1
Epitope
N-Term
11
8
7
7
7
4
2
2
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
67
44
32
5
4
4
4
3
3
3
3
2
2
2
2
Host
Rabbit
59
7
1
Clonality
Polyclonal
Conjugate
This DR1 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
54
25
18
13
7
4
2
1
1
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human DR1
Sequence MASSSGNDDD LTIPRAAINK MIKETLPNVR VANDARELVV NCCTEFIHLI
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Characteristics This is a rabbit polyclonal antibody against DR1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Plasmids, Primers & others Plasmids, Primers & others DR1 products on genomics-online (e.g. as negative or positive controls)
Alternative Name DR1 (DR1 Antibody Abstract)
Background DR1 is a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. DR1 is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. DR1 contains a histone fold motif
Alias Symbols: NC2, NC2-BETA
Protein Interaction Partner: POLE3, TBP, UBC, BTF3L4, LRSAM1, GOPC, NPLOC4, IPO11, DBNL, ARIH1, TTLL12, ARPC1B, UBE3A, METTL1, HSF1, XPO1, YEATS2, DRAP1, CREB1, CCDC101, TADA2B, SUPT20H, MBIP, WDR5, TADA3, KAT2B, MAP3K7, TADA2A, KAT2A, DR1, ELAVL1, NFYC, NFIL3, TTF2, IRF1,
Protein Size: 176
Molecular Weight 19 kDa
Gene ID 1810
NCBI Accession NM_001938, NP_001929
UniProt Q01658
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 176 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (N-Term) antibody (ABIN2780386) WB Suggested Anti-DR1 Antibody Titration: 1.25ug/ml ELISA Titer: 1:62500 Positive...
Product cited in: Deng, Malecová, Oelgeschläger, Roberts: "TFIIB recognition elements control the TFIIA-NC2 axis in transcriptional regulation." in: Molecular and cellular biology, Vol. 29, Issue 6, pp. 1389-400, 2009 (PubMed).

Background publications Gilfillan, Stelzer, Piaia, Hofmann, Meisterernst: "Efficient binding of NC2.TATA-binding protein to DNA in the absence of TATA." in: The Journal of biological chemistry, Vol. 280, Issue 7, pp. 6222-30, 2005 (PubMed).

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