DR1 antibody (N-Term)

Catalog No. ABIN2780386

This Rabbit Polyclonal antibody specifically detects DR1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Horse, Rabbit and Guinea Pig.It has been mentioned in 1 publication

Quick Overview for DR1 antibody (N-Term) (ABIN2780386)

Target: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DR1 Antibody

Binding Specificity: N-Term

Purpose: DR1 Antibody - N-terminal region

Sequence: MASSSGNDDD LTIPRAAINK MIKETLPNVR VANDARELVV NCCTEFIHLI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against DR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DR1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8113522

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-DR1 antibody (ABIN2780386)

Deng, Malecová, Oelgeschläger, Roberts: "TFIIB recognition elements control the TFIIA-NC2 axis in transcriptional regulation." in: Molecular and cellular biology, Vol. 29, Issue 6, pp. 1389-400, (2009) (PubMed).

Target Details for DR1

Target: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Alternative Name: DR1

Background:

Background Information: DR1 is a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. DR1 is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. DR1 contains a histone fold motif

Gene Name: Down-regulator of transcription 1, TBP-binding (negative cofactor 2)

Alternative Symbols: NC2, NC2B, NCB2, NC2-BETA

Protein Name: Protein Dr1

Molecular Weight: 19kDa

Gene ID: 1810

NCBI Accession: NP_001929

UniProt: Q01658