Angiomotin antibody (pSer1041)

Catalog No. ABIN1539757

This Rabbit Polyclonal antibody specifically detects Angiomotin in DB. It exhibits reactivity toward Human.

Quick Overview for Angiomotin antibody (pSer1041) (ABIN1539757)

Target: Angiomotin (AMOT)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiomotin antibody is un-conjugated

Application: Dot Blot (DB)

Clone: RB40428

Product Details anti-Angiomotin Antibody

Binding Specificity: pSer1041

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AMOT Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1041 of human AMOT.

Isotype: Ig Fraction

Application Details

Application Notes: DB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Phospho-AMOT-S1041 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for Angiomotin

Target: Angiomotin (AMOT)

Alternative Name: AMOT

Background: This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 118085

Gene ID: 154796

NCBI Accession: NP_001106962, NP_573572

UniProt: Q4VCS5

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size