CST3 antibody (AA 95-122)

Catalog No. ABIN1539956

The Mouse Monoclonal anti-CST3 antibody has been validated for WB. It is suitable to detect CST3 in samples from Human.

Quick Overview for CST3 antibody (AA 95-122) (ABIN1539956)

Target: CST3 (Cystatin C (CST3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CST3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 572CT4-3-2

Product Details anti-CST3 Antibody

Binding Specificity: AA 95-122

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This CST3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 95-122 amino acids from human CST3.

Isotype: IgG1

Application Details

Application Notes: WB: 1:100~800

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CST3 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for CST3

Target: CST3 (Cystatin C (CST3))

Alternative Name: CST3

Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease.

Molecular Weight: 15799

Gene ID: 1471

NCBI Accession: NP_000090

UniProt: P01034