Cyclic GMP antibody

Catalog No. ABIN155131

This Rabbit Polyclonal antibody specifically detects Cyclic GMP in EIA. It exhibits reactivity toward .

Quick Overview for Cyclic GMP antibody (ABIN155131)

Target: Cyclic GMP (cGMP)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclic GMP antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Product Details anti-Cyclic GMP Antibody

Purification: Affinity purified

Immunogen: 2'O-succinyl guanosine-3',5' cyclic monophosphate (cyclic GMP, cGMP).

Application Details

Application Notes: 1: 10-50 dilutions for nonradioactive EIA assays (10 μL/assay in an 70 μL assay reaction). The material is sufficient for performing 100-500 nonradioactive EIA assays or 6,000 radioactive assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.02 % Thimerosal, 50 % Glycerol, 1 % BSA

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for Cyclic GMP

Target: Cyclic GMP (cGMP)

Alternative Name: Cyclic GMP

Target Type: Chemical

Background: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).Synonyms: cGMP, cyclic guanosine monophosphate