ADNP antibody (AA 843-1102)

Catalog No. ABIN1678582

This Rabbit Polyclonal antibody specifically detects ADNP in WB and IF. It exhibits reactivity toward Human.

Quick Overview for ADNP antibody (AA 843-1102) (ABIN1678582)

Target: ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADNP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ADNP Antibody

Binding Specificity: AA 843-1102

Sequence: EWLFENHDEK DSRVNASKTA DKKLNLGKED DSSSDSFENL EEESNESGSP FDPVFEVEPK ISNDNPEEHV LKVIPEDASE SEEKLDQKED GSKYETIHLT EEPTKLMHNA SDSEVDQDDV VEWKDGASPS ESGPGSQQVS DFEDNTCEMK PGTWSDESSQ SEDARSSKPA AKKKATMQGD REQLKWKNSS YGKVEGFWSK DQSQWKNASE NDERLSNPQI EWQNSTIDSE DGEQFDNMTD GVAEPMHGSL AGVKLSSQQA

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 843-1102 of human ADNP (NP_056154.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ADNP

Target: ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))

Alternative Name: ADNP

Background: Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.,ADNP,ADNP1,HVDAS,MRD28,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,ADNP

Molecular Weight: 123 kDa

Gene ID: 23394

UniProt: Q9H2P0

Pathways: Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process