alpha 1 Adrenergic Receptor antibody (AA 346-475)

Catalog No. ABIN1678588

This Rabbit Polyclonal antibody specifically detects alpha 1 Adrenergic Receptor in WB, IF and IHC. It exhibits reactivity toward Human.

Quick Overview for alpha 1 Adrenergic Receptor antibody (AA 346-475) (ABIN1678588)

Target: alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha 1 Adrenergic Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-alpha 1 Adrenergic Receptor Antibody

Binding Specificity: AA 346-475

Sequence: LCRKQSSKHA LGYTLHPPSQ AVEGQHKDMV RIPVGSRETF YRISKTDGVC EWKFFSSMPR GSARITVSKD QSSCTTARTK SRSVTRLECS GMILAHCNLR LPGSRDSPAS ASQAAGTTGM CHQADATRPS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 346-475 of human ADRA1A (NP_150646.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for alpha 1 Adrenergic Receptor

Target: alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))

Alternative Name: ADRA1A

Background: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.,ADRA1A,ADRA1C,ADRA1L1,ALPHA1AAR,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,AMPK Signaling Pathway,Neuroscience,ADRA1A

Molecular Weight: 32-52 kDa

Gene ID: 148

UniProt: P35348

Pathways: AMPK Signaling