Activin A Receptor Type IB/ALK-4 antibody

Catalog No. ABIN1678826

The Rabbit Monoclonal anti-Activin A Receptor Type IB/ALK-4 antibody has been validated for WB, IHC and IF. It is suitable to detect Activin A Receptor Type IB/ALK-4 in samples from Human.

Quick Overview for Activin A Receptor Type IB/ALK-4 antibody (ABIN1678826)

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Activin A Receptor Type IB/ALK-4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Activin A Receptor Type IB/ALK-4 Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human ACVR1B

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Activin A Receptor Type IB/ALK-4

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Alternative Name: ACVR1B

Background: This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010],ACTRIB, ACVRLK4, ALK4, SKR2,Apoptosis,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Signal Transduction,Stem Cells,ACVR1B

Molecular Weight: 52 kDa

Gene ID: 91

UniProt: P36896