Biglycan antibody (AA 20-230)
Quick Overview for Biglycan antibody (AA 20-230) (ABIN1678858)
Target
See all Biglycan (BGN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 20-230
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Sequence
- EQRGFWDFTL DDGPFMMNDE EASGADTSGV LDPDSVTPTY SAMCPFGCHC HLRVVQCSDL GLKSVPKEIS PDTTLLDLQN NDISELRKDD FKGLQHLYAL VLVNNKISKI HEKAFSPLRK LQKLYISKNH LVEIPPNLPS SLVELRIHDN RIRKVPKGVF SGLRNMNCIE MGGNPLENSG FEPGAFDGLK LNYLRISEAK LTGIPKDLPE T
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Cross-Reactivity
- Human
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-230 of human BGN (NP_001702.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:1000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Biglycan (BGN)
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Alternative Name
- BGN
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Background
- This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication.,BGN,DSPG1,MRLS,PG-S1,PGI,SEMDX,SLRR1A,biglycan,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,Stem Cells,Mesenchymal Stem Cells,BGN
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Molecular Weight
- 41 kDa
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Gene ID
- 633
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UniProt
- P21810
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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