CTBP2 antibody (C-Term)

Catalog No. ABIN1679396

The Rabbit Polyclonal anti-CTBP2 antibody has been validated for WB and IF. It is suitable to detect CTBP2 in samples from Human. There is 1 publication available.

Quick Overview for CTBP2 antibody (C-Term) (ABIN1679396)

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTBP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-CTBP2 Antibody

Binding Specificity: C-Term

Sequence: SEPFSFAQGP LKDAPNLICT PHTAWYSEQA SLEMREAAAT EIRRAITGRI PESLRNCVNK EFFVTSAPWS VIDQQAIHPE LNGATYRYPP GIVGVAPGGL PAAMEGIIPG GIPVTHNLPT VAHPSQAPSP NQPTKHGDNR EHPNEQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human CTBP2 (NP_001320.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-CTBP2 antibody (ABIN1679396)

Li, Liu, He, Yang, Pei, Li, Liu, Chen, Xie, Xu, Ting, Zhang, Jin, Liu, Zhang, Yuan, Yang, Wu, Zhang, Yang, Yi, Liang, Shang, Sun: "ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin." in: Nature communications, Vol. 8, Issue 1, pp. 691, (2018) (PubMed).

Target Details for CTBP2

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Alternative Name: CTBP2

Background: This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3, however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene.,CTBP2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Notch Signaling Pathway,Neuroscience,Cell Type Marker,Neuron marker,Synapse marker,CTBP2

Molecular Weight: 48 kDa/56 kDa/106 kDa

Gene ID: 1488

UniProt: P56545