CYLD antibody (AA 654-953)

Catalog No. ABIN1679467

This Rabbit Polyclonal antibody specifically detects CYLD in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for CYLD antibody (AA 654-953) (ABIN1679467)

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYLD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CYLD Antibody

Binding Specificity: AA 654-953

Sequence: TKIMKLRKIL EKVEAASGFT SEEKDPEEFL NILFHHILRV EPLLKIRSAG QKVQDCYFYQ IFMEKNEKVG VPTIQQLLEW SFINSNLKFA EAPSCLIIQM PRFGKDFKLF KKIFPSLELN ITDLLEDTPR QCRICGGLAM YECRECYDDP DISAGKIKQF CKTCNTQVHL HPKRLNHKYN PVSLPKDLPD WDWRHGCIPC QNMELFAVLC IETSHYVAFV KYGKDDSAWL FFDSMADRDG GQNGFNIPQV TPCPEVGEYL KMSLEDLHSL DSRRIQGCAR RLLCDAYMCM YQSPTMSLYK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 654-953 of human CYLD (NP_001035877.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CYLD

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Alternative Name: CYLD

Background: This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,CYLD,BRSS,CDMT,CYLD1,CYLDI,EAC,MFT,MFT1,SBS,TEM,USPL2,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Ubiquitin,Death Receptor Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,CYLD

Molecular Weight: 107 kDa

Gene ID: 1540

UniProt: Q9NQC7

Pathways: Apoptosis, Activation of Innate immune Response