DRG1 antibody (AA 158-367)

Catalog No. ABIN1679602

This Rabbit Polyclonal antibody specifically detects DRG1 in WB. It exhibits reactivity toward Human.

Quick Overview for DRG1 antibody (AA 158-367) (ABIN1679602)

Target: DRG1 (Developmentally Regulated GTP Binding Protein 1 (DRG1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRG1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DRG1 Antibody

Binding Specificity: AA 158-367

Sequence: KKIIENELEG FGIRLNSKPP NIGFKKKDKG GINLTATCPQ SELDAETVKS ILAEYKIHNA DVTLRSDATA DDLIDVVEGN RVYIPCIYVL NKIDQISIEE LDIIYKVPHC VPISAHHRWN FDDLLEKIWD YLKLVRIYTK PKGQLPDYTS PVVLPYSRTT VEDFCMKIHK NLIKEFKYAL VWGLSVKHNP QKVGKDHTLE DEDVIQIVKK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 158-367 of human DRG1 (NP_004138.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DRG1

Target: DRG1 (Developmentally Regulated GTP Binding Protein 1 (DRG1))

Alternative Name: DRG1

Background: Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions. When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation. Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions.,DRG1,NEDD3,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,DRG1

Molecular Weight: 40 kDa

Gene ID: 4733

UniProt: Q9Y295