FMR1 antibody

Catalog No. ABIN1679778

This anti-FMR1 antibody is a Rabbit Monoclonal antibody detecting FMR1 in WB and IHC. Suitable for Human.

Quick Overview for FMR1 antibody (ABIN1679778)

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FMR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FMR1 Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human FMRP

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FMR1

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Alternative Name: FMR1

Background: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010],FMRP, FRAXA, POF, POF1,Cell Type Marker,Cell Type Marker_Dendrite marker,Cell Type Marker_Neuron marker,Cell Type Marker_Synapse marker,Epigenetics & Nuclear Signaling,Neurodegenerative Diseases,Neuroscience,RNA Binding,FMR1

Molecular Weight: 58 kDa/61 kDa/66 kDa/68 kDa/69 kDa/70 kDa/71 kDa

Gene ID: 2332

UniProt: Q06787

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development