FLNB antibody (AA 1686-1785)

Catalog No. ABIN1679857

This Rabbit Polyclonal antibody specifically detects FLNB in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for FLNB antibody (AA 1686-1785) (ABIN1679857)

Target: FLNB (Filamin B, beta (FLNB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLNB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FLNB Antibody

Binding Specificity: AA 1686-1785

Sequence: PDGTEAEADV IENEDGTYDI FYTAAKPGTY VIYVRFGGVD IPNSPFTVMA TDGEVTAVEE APVNACPPGF RPWVTEEAYV PVSDMNGLGF KPFDLVIPFA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1686-1785 of human FLNB (NP_001157789.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IHC,1:50 - 1:100,IF,1:20 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FLNB

Target: FLNB (Filamin B, beta (FLNB))

Alternative Name: FLNB

Background: This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.,FLNB,ABP-278,ABP-280,AOI,FH1,FLN-B,FLN1L,LRS1,SCT,TABP,TAP,filamin-B,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,FLNB

Molecular Weight: 230-281 kDa

Gene ID: 2317

UniProt: O75369

Pathways: Maintenance of Protein Location