GCLC antibody
Quick Overview for GCLC antibody (ABIN1680604)
Target
See all GCLC AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Rat
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthesized peptide derived from human GCLC
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Isotype
- IgG
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anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 528-637) antibody
GCLC Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 3H1 unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 1-30), (N-Term) antibodyGCLC Reactivity: Human WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB31687 unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (N-Term) antibodyGCLC Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Rabbit, Dog, Guinea Pig, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 1-30) antibodyGCLC Reactivity: Human WB, IHC, ELISA, IF, FACS Host: Rabbit Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (N-Term) antibodyGCLC Reactivity: Human, Mouse, Rat, Pig WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 437-637) antibodyGCLC Reactivity: Human, Mouse, Rat WB, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 1-252) antibodyGCLC Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 435-636) antibodyGCLC Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (Middle Region) antibodyGCLC Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Rabbit, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 6-34), (N-Term) antibodyGCLC Reactivity: Human WB, IF, FACS, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
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Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
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Alternative Name
- GCLC
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Background
- Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010],GCL, GCS, GLCL, GLCLC,Apoptosis,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Signal Transduction,GCLC
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Molecular Weight
- 73 kDa
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Gene ID
- 2729
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UniProt
- P48506
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Pathways
- Cell RedoxHomeostasis
Target
-
