MXD1 antibody (AA 1-221)

Catalog No. ABIN1680937

This Rabbit Polyclonal antibody specifically detects MXD1 in WB. It exhibits reactivity toward Human.

Quick Overview for MXD1 antibody (AA 1-221) (ABIN1680937)

Target: MXD1 (MAX Dimerization Protein 1 (MXD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MXD1 Antibody

Binding Specificity: AA 1-221

Sequence: MAAAVRMNIQ MLLEAADYLE RREREAEHGY ASMLPYNNKD RDALKRRNKS KKNNSSSRST HNEMEKNRRA HLRLCLEKLK GLVPLGPESS RHTTLSLLTK AKLHIKKLED CDRKAVHQID QLQREQRHLK RQLEKLGIER IRMDSIGSTV SSERSDSDRE EIDVDVESTD YLTGDLDWSS SSVSDSDERG SMQSLGSDEG YSSTSIKRIK LQDSHKACLG L

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human MXD1 (NP_002348.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MXD1

Target: MXD1 (MAX Dimerization Protein 1 (MXD1))

Alternative Name: MXD1

Background: This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,MXD1,BHLHC58,MAD,MAD1,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-Erk Signaling Pathway,MXD1

Molecular Weight: 24 kDa/25 kDa

Gene ID: 4084

UniProt: Q05195