Tumor Protein p73 antibody (pTyr99)

Catalog No. ABIN3020529

This Rabbit Polyclonal antibody specifically detects Tumor Protein p73 in WB. It exhibits reactivity toward Human.

Quick Overview for Tumor Protein p73 antibody (pTyr99) (ABIN3020529)

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tumor Protein p73 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Tumor Protein p73 Antibody

Binding Specificity: pTyr99

Cross-Reactivity: Human

Characteristics: Phosphorylated Antibodies

Immunogen: A phospho specific peptide corresponding to residues surrounding Y99 of human TP73

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Tumor Protein p73

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Alternative Name: TP73

Background: This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.,TP73,P73,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,Hippo Signaling Pathway,Protein phosphorylation,TP73

Molecular Weight: 38- 69 kDa

Gene ID: 7161

UniProt: O15350

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus